U 90042

Name: U 90042
Brand: Tocris Bioscience
SKU: 2733

Tocris Bioscience a Bio-Techne Brand

Catalog # 2733

COA / SDS

Discontinued Product

2733 has been discontinued. View all GABA-A Receptor Modulators products.

Key Product Details

Description:	GABA_A ligand
Chemical Name:	11-Chloro-5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2,3-dihydrodiimidazo[1,5-a:1',2'-c]quinazoline
Purity:	≥99% (HPLC)
Molecular Weight:	352.78

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Biological Activity for U 90042

U 90042 is a GABA_A receptor ligand that binds with comparable affinities to three receptor subtypes: α₁β₂γ₂, α₃β₂γ₂ and α₆β₂γ₂ (K_i values are 7.8, 9.5 and 11.0 nM respectively). Potentiates GABA-induced chloride currents in α₆β₂γ₂ receptors. Sedative/hypnotic compound.

Technical Data for U 90042

M. Wt	352.78
Formula	C₁₇H₁₃ClN₆O
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	134516-99-7
PubChem ID	9928470
InChi Key	CLPSAAPUJUVQPP-UHFFFAOYSA-N
Smiles	ClC1=CC=C4C(C2=NCCN2C(N4C=N5)=C5C3=NOC(C6CC6)=N3)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for U 90042

References are publications that support the biological activity of the product.

Tang U-90042, a sedative/hypnotic compound that interacts differentially with the GABA_A receptor subtypes. J.Pharmacol.Exp.Ther. 1995 PMID: 7473164

Citations for U 90042

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U 90042

Tocris Bioscience a Bio-Techne Brand

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Biological Activity for U 90042

Technical Data for U 90042

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References for U 90042

Citations for U 90042

Product Documents for U 90042

COA

Certificate of Analysis

SDS

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