Tropanyl-3,5-dimethylbenzoate

Name: Tropanyl-3,5-dimethylbenzoate
Brand: tocris
SKU: 0641

Catalog # 0641

Citations (2)

Datasheet / COA / SDS

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Key Product Details

Description:	5-HT₃ antagonist
Purity:	≥99%
Molecular Weight:	273.37

View Full Technical Details for Tropanyl-3,5-dimethylbenzoate

Biological Activity

5-HT₃ antagonist.

Technical Data

M. Wt	273.37
Formula	C₁₇H₂₃NO₂
Storage	Store at RT
Purity	≥99%
CAS Number	85181-40-4
PubChem ID	2837530
InChi Key	HDDNYFLPWFSBLN-UHFFFAOYSA-N
Smiles	CN1C2CCC1CC(C2)OC(=O)C1=CC(C)=CC(C)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	13.67	50

Preparing Stock Solutions

The following data is based on the product molecular weight 273.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	7.32 mL	36.58 mL	73.16 mL
2.5 mM	1.46 mL	7.32 mL	14.63 mL
5 mM	0.73 mL	3.66 mL	7.32 mL
25 mM	0.15 mL	0.73 mL	1.46 mL

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References

References are publications that support the biological activity of the product.

Fozard and Gitto Selective blockade of 5-hydroxytryptamine neuronal receptors by benzoic acid esters of tropine. Br.J.Pharmacol.

Citations (2)

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Citations are publications that use Bio-Techne products. Selected citations for Tropanyl-3,5-dimethylbenzoate include:

Dolma et al. (2016) Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell. 29:859
PMID: 27300435
Yang et al. (2010) Activation of submucosal 5-HT(3) receptors elicits a somatostatin-dependent inhibition of ion secretion in rat colon. Br J Pharmacol. 159:1623
PMID: 20233224

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Product Datasheets

COA

Certificate of Analysis

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SDS

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Tropanyl-3,5-dimethylbenzoate

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References

Citations (2)

Product Datasheets

COA

Certificate of Analysis

SDS

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