(S)-Timolol maleate

Name: ( S )-Timolol maleate
Brand: Tocris Bioscience
SKU: 0649

Tocris Bioscience a Bio-Techne Brand

Catalog # 0649

Citations (1)

COA / SDS

Discontinued Product

0649 has been discontinued. View all Adrenergic beta-1 Receptor Antagonists products.

Key Product Details

Description:	β₁ antagonist
Chemical Name:	(S)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol maleate
Molecular Weight:	432.49

View Full Technical Details for (S)-Timolol maleate

Biological Activity for (S)-Timolol maleate

(S)-Timolol maleate is an β₁-adrenergic blocker.

Technical Data for (S)-Timolol maleate

M. Wt	432.49
Formula	C₁₃H₂₄N₄O₃S.C₄H₄O₄
Storage	Store at RT
CAS Number	26921-17-5
PubChem ID	5281056
InChi Key	WLRMANUAADYWEA-NWASOUNVSA-N
Smiles	[H]OC(=O)\C=C/C(=O)O[H].CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (S)-Timolol maleate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions for (S)-Timolol maleate

The following data is based on the product molecular weight 432.49.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.31 mL	11.56 mL	23.12 mL
5 mM	0.46 mL	2.31 mL	4.62 mL
10 mM	0.23 mL	1.16 mL	2.31 mL
50 mM	0.05 mL	0.23 mL	0.46 mL

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Reconstitution Calculator

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References for (S)-Timolol maleate

References are publications that support the biological activity of the product.

Karhuvaara β-Adrenoceptor antagonist activities and binding affinities of tim. enantiomers in rat atria. J.Pharm.Pharmacol. 1989 PMID: 2573714

Citations for (S)-Timolol maleate (1)

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Citations are publications that use Bio-Techne products. Selected citations for (S)-Timolol maleate include:

Xiao et al. (2019) Acute tobacco smoke exposure exacerbates the inflammatory response to corneal wounds in mice via the sympathetic nervous system. Commun Biol. 2:33
PMID: 30701198

There are no citations that match your criteria.