(S)-Timolol maleate

Name: ( S )-Timolol maleate
Brand: tocris
SKU: 0649

Catalog # 0649

Citations (1)

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Key Product Details

Description:	β₁ antagonist
Chemical Name:	(S)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol maleate
Molecular Weight:	432.49

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Biological Activity

(S)-Timolol maleate is an β₁-adrenergic blocker.

Technical Data

M. Wt	432.49
Formula	C₁₃H₂₄N₄O₃S.C₄H₄O₄
Storage	Store at RT
CAS Number	26921-17-5
PubChem ID	5281056
InChi Key	WLRMANUAADYWEA-NWASOUNVSA-N
Smiles	[H]OC(=O)\C=C/C(=O)O[H].CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions

The following data is based on the product molecular weight 432.49.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.31 mL	11.56 mL	23.12 mL
5 mM	0.46 mL	2.31 mL	4.62 mL
10 mM	0.23 mL	1.16 mL	2.31 mL
50 mM	0.05 mL	0.23 mL	0.46 mL

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References

References are publications that support the biological activity of the product.

Karhuvaara β-Adrenoceptor antagonist activities and binding affinities of tim. enantiomers in rat atria. J.Pharm.Pharmacol. 1989 PMID: 2573714
Merck Index

Citations (1)

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Citations are publications that use Bio-Techne products. Selected citations for (S)-Timolol maleate include:

Xiao et al. (2019) Acute tobacco smoke exposure exacerbates the inflammatory response to corneal wounds in mice via the sympathetic nervous system. Commun Biol. 2:33
PMID: 30701198

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(S)-Timolol maleate

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References

Citations (1)

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