RC 160

Name: RC 160
Brand: Tocris Bioscience
SKU: 3139

Tocris Bioscience a Bio-Techne Brand

Catalog # 3139

COA / SDS

Discontinued Product

3139 has been discontinued. View all Somatostatin Receptor Agonists products.

Key Product Details

Description:	sst analog
Alternative Names:	Vapreotide
Molecular Weight:	1131.37

View Full Technical Details for RC 160

Biological Activity for RC 160

RC 160 is a cyclic octapeptide somatostatin analog (K_i values are 0.7, 5.4, 30.9, 45 and > 1000 nM for sst₅, sst₂, sst₃, sst₄ and sst₁ receptors respectively). More metabolically stable than somatostatin (Cat. No. 1157). Inhibits growth hormone release in vivo.

Technical Data for RC 160

M. Wt	1131.37
Formula	C₅₇H₇₀N₁₂O₉S₂
Single Letter Sequence	FCYWKVCW (Modifications: Phe-1 = D-Phe, Trp-4 = D-Trp, Trp-8 = C-terminal amide, Disulfide bridge between 2 - 7)
Storage	Desiccate at -20°C
CAS Number	103222-11-3
PubChem ID	6918026
InChi Key	SWXOGPJRIDTIRL-DOUNNPEJSA-N
Smiles	[H]N[C@H](CC1=CC=CC=C1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC1=O)C(C)C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for RC 160

Solubility

Soluble to 0.2mg/ml in water

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References for RC 160

References are publications that support the biological activity of the product.

Lahlou sst2 Somatostatin receptor inhibits cell proliferation through Ras- Rap1-, and B-raf-dependent ERK2 activation. J.Biol.Chem. 2003 PMID: 12878607
Patel and Srikant Subtype selectivity of peptide analogs for all five coned human somatostatin receptors (hsstr 1-5). Endocrinology 1994 PMID: 7988476
Karashima Effects of highly potent octapeptide analogs of somatostatin on GH, Ins and glucagon release. Life Sci. 1987 PMID: 2886886

Citations for RC 160

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RC 160

Tocris Bioscience a Bio-Techne Brand

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Biological Activity for RC 160

Technical Data for RC 160

Solubility for RC 160

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for RC 160

Citations for RC 160

Product Documents for RC 160

COA

Certificate of Analysis

SDS

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