Pronethalol hydrochloride

Name: Pronethalol hydrochloride
Brand: Tocris Bioscience
SKU: 0829

Tocris Bioscience a Bio-Techne Brand

Catalog # 0829

Citations (1)

COA / SDS

Discontinued Product

0829 has been discontinued. View all Non-selective Adrenergic beta Receptor Antagonists products.

Key Product Details

Description:	β antagonist
Alternative Names:	ICI-38174
Chemical Name:	2-Isopropylamino-1-(2-naphthyl)ethanol hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	265.78

View Full Technical Details for Pronethalol hydrochloride

Biological Activity for Pronethalol hydrochloride

Pronethalol hydrochloride is an β-adrenergic antagonist, clinically effective in the treatment of angina pectoris and some arrhythmias.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data for Pronethalol hydrochloride

M. Wt	265.78
Formula	C₁₅H₁₉NO.HCl
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	51-02-5
PubChem ID	60975
InChi Key	QONLGXRPRAIDGI-UHFFFAOYSA-N
Smiles	Cl.CC(C)NCC(O)C1=CC=C2C=CC=CC2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Pronethalol hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions for Pronethalol hydrochloride

The following data is based on the product molecular weight 265.78.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.76 mL	18.81 mL	37.63 mL
5 mM	0.75 mL	3.76 mL	7.53 mL
10 mM	0.38 mL	1.88 mL	3.76 mL
50 mM	0.08 mL	0.38 mL	0.75 mL

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Reconstitution Calculator

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References for Pronethalol hydrochloride

References are publications that support the biological activity of the product.

Main α-Adrenergic receptors. Comprehensive Medicinal Chemistry. Ed Hansch

Citations for Pronethalol hydrochloride (1)

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Citations are publications that use Bio-Techne products. Selected citations for Pronethalol hydrochloride include:

Kaya et al. (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. J Pharmacol Exp Ther. 329:350
PMID: 19144685

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