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PMPA (NMDA antagonist)

Tocris Bioscience a Bio-Techne Brand

NMDA Receptor Antagonists Small Molecule
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Key Product Details

Description: Competitive NMDA antagonist
Alternative Names: PMPC
Chemical Name: 4-(Phosphonomethyl)-2-piperazinecarboxylic acid
Molecular Weight: 224.15

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  • Antagonism at NMDA receptor
    Name: Sergiy Sylantyev
    Species: Human
    PMPA was in use as an NMDA receptor antagonist affecting glutamate site, to study (possible) competition of dopamine for this site. Application of PMPA and dopamine mixtures in different ratios resulted in a decrease of single-channel NMDA receptor openings recorded from outside-out neuron membrane patches. No problem with dissolution in water up to 10 mM concentration.
    PMPA (NMDA antagonist) Serum 2273

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Product Documents for PMPA (NMDA antagonist)

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