Pirlindole mesylate

Name: Pirlindole mesylate
Brand: tocris
SKU: 0724

Catalog # 0724

Citations (1)

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Key Product Details

Description:	MAO-A inhibitor
Chemical Name:	2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino[3,2,1-j,k]carbazole mesylate
Molecular Weight:	322.42

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Biological Activity

Pirlindole mesylate is a highly selective reversible inhibitor of monoamine oxidase type A.

Technical Data

M. Wt	322.42
Formula	C₁₅H₁₈N₂.CH₃SO₃H
Storage	Store at RT
CAS Number	207572-66-5
PubChem ID	2829432
InChi Key	PVUYTBQAVAYLDE-UHFFFAOYSA-N
Smiles	CS(O)(=O)=O.CC1=CC=C2N3CCNC4CCCC(C2=C1)=C34

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	16.12	50 with gentle warming

Preparing Stock Solutions

The following data is based on the product molecular weight 322.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	6.20 mL	31.02 mL	62.03 mL
2.5 mM	1.24 mL	6.20 mL	12.41 mL
5 mM	0.62 mL	3.10 mL	6.20 mL
25 mM	0.12 mL	0.62 mL	1.24 mL

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References

References are publications that support the biological activity of the product.

Mashkovsky and Andreeva Pharmacological properties of 2,3,3α,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-j,k]carbazole hydrochloride (pirlindole), a new antidepressant. Arzneim.-Forsch.Drug Res. 1981 PMID: 7194096
Medvedev Efficacy of pirlindole, a highly selective reversible inhibitor of monoamine oxidase type A in the prevention of experimentally induced epiletic seizures. Drug Investigation.

Citations (1)

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Citations are publications that use Bio-Techne products. Selected citations for Pirlindole mesylate include:

Njagi et al. (2010) Electrochemical quantification of serotonin in the live embryonic zebrafish intestine. Anal Chem. 82:1822
PMID: 20148518

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Pirlindole mesylate

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