PG-9 maleate

Name: PG-9 maleate
Brand: tocris
SKU: 0750

Catalog # 0750

Datasheet / COA / SDS

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Key Product Details

Description:	Presynaptic cholinergic modulator
Chemical Name:	Tropanyl 2-(4-bromophenyl)propionate maleate
Molecular Weight:	468.34

View Full Technical Details for PG-9 maleate

Technical Data
Citations / Reviews

Biological Activity

A potent analgesic and nootropic agent. Increases release of acetylcholine.

Technical Data

M. Wt	468.34
Formula	C₁₇H₂₂BrNO₂.C₄H₄O₄
Storage	Store at RT
CAS Number	155649-00-6
PubChem ID	46905315
InChi Key	VBUSCULTLLOSLM-BTJKTKAUSA-N
Smiles	OC(=O)\C=C/C(O)=O.CC(C(=O)OC1CC2CCC(C1)N2C)C1=CC=C(Br)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	46.83	100

Preparing Stock Solutions

The following data is based on the product molecular weight 468.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.14 mL	10.68 mL	21.35 mL
5 mM	0.43 mL	2.14 mL	4.27 mL
10 mM	0.21 mL	1.07 mL	2.14 mL
50 mM	0.04 mL	0.21 mL	0.43 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Ghelardini Antinociceptive and antiamnesic properties of the presynaptic cholinergic amplifier PG-9. J.Pharmacol.Exp.Ther. 1998 PMID: 9495837
Gualtieri Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 1. Tropic and 2-phenylpropionic acid esters. J.Med.Chem. 1994 PMID: 8201605