NocII

Name: NocII
Brand: Tocris Bioscience
SKU: 1119

Tocris Bioscience a Bio-Techne Brand

Catalog # 1119

Citations (2)

COA / SDS

Discontinued Product

1119 has been discontinued. View all Additional NOP Receptor Peptides products.

Key Product Details

Description:	Orphan neuropeptide
Molecular Weight:	2081.4

View Full Technical Details for NocII

Biological Activity for NocII

NocII is an orphan neuropeptide, flanking nociceptin in the precursor pronociceptin. Stimulates locomotion in mice, possibly through a novel specific receptor.

Technical Data for NocII

M. Wt	2081.4
Formula	C₉₂H₁₄₁N₂₃O₂₈S₂
Single Letter Sequence	FSEFMRQYLVLSMQSSQ
Storage	Desiccate at -20°C
CAS Number	188119-47-3
PubChem ID	90479756
InChi Key	PPKKOTLGXBHLAB-XVHSACDVSA-N
Smiles	[H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for NocII

References are publications that support the biological activity of the product.

Florin Comparison of behavioural effects of NocII or NocIII, two related pronociceptin-derived peptides. Life Sci. 1999 PMID: 10622282
Florin Orphan neuropeptide NocII, a putative pronociceptin maturation product, stimulates locomotion in mice. NeuroReport 1997 PMID: 9106751

Citations for NocII (2)

Showing 1 - 2 of 2 citations Showing All

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Citations are publications that use Bio-Techne products. Selected citations for NocII include:

Krokowski (2017) GADD34 function in protein trafficking promotes adaptation to hyperosmotic stress in human corneal cells. Cell Rep. 21(10):2895
PMID: 29212034
Laudenbach et al. (2001) Nociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brain. J Clin Invest. 107:457
PMID: 11181645

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Product Documents for NocII

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.