MPDC

Name: MPDC
Brand: tocris
SKU: 0973

Catalog # 0973

Datasheet / COA / SDS

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Bio-Techne Corporation

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Shipping Information

$35 to United States

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Key Product Details

Description:	Potent inhibitor of L-glutamate uptake. Less activity as a substrate compared to its parent compound, L-trans-2,4-PDC (Cat. No. 0298)
Chemical Name:	L-anti-endo-3,4-Methanopyrrolidinedicarboxylic acid

View Full Technical Details for MPDC

Biological Activity

Potent inhibitor of the Na⁺-dependent high-affinity synaptosomal glutamate transporter.

Technical Data

M. Wt	171.15
Formula	C₇H₉NO₄
Storage	Store at RT
CAS Number	159262-32-5
PubChem ID	6604785
InChi Key	UNNFLFDQCHJXPI-QTBDOELSSA-N
Smiles	[H][C@]1([C@H]2[C@@](O)=O)[C@]2([H])CN[C@@H]1[C@](O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions

The following data is based on the product molecular weight 171.15.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.84 mL	29.21 mL	58.43 mL
5 mM	1.17 mL	5.84 mL	11.69 mL
10 mM	0.58 mL	2.92 mL	5.84 mL
50 mM	0.12 mL	0.58 mL	1.17 mL

Molarity Calculator

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Bridges A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: L-anti-endo-3,4-methanopyrrolidine carboxylate. Neurosci.Lett. 1994 PMID: 7970177