MM 77 dihydrochloride

Name: MM 77 dihydrochloride
Brand: tocris
SKU: 0933

Catalog # 0933

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

tel: (612) 379-2956

tel: (800) 343-7475 (free phone)

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

View Distributors

Key Product Details

Description:	5-HT_1A (postsynaptic) antagonist
Chemical Name:	1-(2-Methoxyphenyl)-4-(4-succinimidobutyl)piperazine dihydrochloride
Molecular Weight:	418.36

View Full Technical Details for MM 77 dihydrochloride

Biological Activity

A highly potent and fairly selective 5-HT_1A ligand, which may be a full antagonist at postsynaptic receptors.

Technical Data

M. Wt	418.36
Formula	C₁₉H₂₇N₃O₃.2HCl
Storage	Store at RT
CAS Number	159187-70-9
PubChem ID	45073441
InChi Key	ZYCVVOZXHNDRCO-UHFFFAOYSA-N
Smiles	Cl.Cl.COC1=CC=CC=C1N1CCN(CCCCN2C(=O)CCC2=O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	31.38	75

Preparing Stock Solutions

The following data is based on the product molecular weight 418.36.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.75 mM	3.19 mL	15.94 mL	31.87 mL
3.75 mM	0.64 mL	3.19 mL	6.37 mL
7.5 mM	0.32 mL	1.59 mL	3.19 mL
37.5 mM	0.06 mL	0.32 mL	0.64 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References

References are publications that support the biological activity of the product.

Mokrosz 1-(2-Methoxyphenyl)-4-(4-succinimidobutyl)piperazine (MM 77): a new, potent, postsynaptic antagonist of 5-HT_1A receptors. Med.Chem.Res.