Methyl 2,5-dihydroxycinnamate

Name: Methyl 2,5-dihydroxycinnamate
Brand: tocris
SKU: 0577

Catalog # 0577

Datasheet / COA / SDS

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Key Product Details

Description:	EGFR-kinase inhibitor
Alternative Names:	Erbstatin analog
Purity:	≥98% (HPLC)
Molecular Weight:	194.19

View Full Technical Details for Methyl 2,5-dihydroxycinnamate

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Biological Activity

Methyl 2,5-dihydroxycinnamate is an erbstatin analog. Inhibitor of EGF receptor-associated tyrosine kinases.

Technical Data

M. Wt	194.19
Formula	C₁₀H₁₀O₄
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	63177-57-1
PubChem ID	5353609
InChi Key	BQCNSTFWSKOWMA-GORDUTHDSA-N
Smiles	COC(=O)\C=C\C1=C(O)C=CC(O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	ethanol		100

Preparing Stock Solutions

The following data is based on the product molecular weight 194.19.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.15 mL	25.75 mL	51.50 mL
5 mM	1.03 mL	5.15 mL	10.30 mL
10 mM	0.51 mL	2.57 mL	5.15 mL
50 mM	0.10 mL	0.51 mL	1.03 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Isshiki Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors. FEBS Lett. 1990 PMID: 2298299