L-Serine

Name: L-Serine
Brand: tocris
SKU: 0227

Catalog # 0227

Citations (1)

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Key Product Details

Description:	Weak endogenous glycine receptor agonist
Chemical Name:	β-Hydroxyalanine
Purity:	≥99% (HPLC)
Molecular Weight:	105.09

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Technical Data
Citations (1) / Reviews

Biological Activity

Endogenous agonist at the inhibitory glycine receptor.

D-isomer also available.

Technical Data

M. Wt	105.09
Formula	C₃H₇NO₃
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	56-45-1
PubChem ID	5951
InChi Key	MTCFGRXMJLQNBG-REOHCLBHSA-N
Smiles	OC[C@]([H])(N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions

The following data is based on the product molecular weight 105.09.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	9.52 mL	47.58 mL	95.16 mL
5 mM	1.90 mL	9.52 mL	19.03 mL
10 mM	0.95 mL	4.76 mL	9.52 mL
50 mM	0.19 mL	0.95 mL	1.90 mL

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References

References are publications that support the biological activity of the product.

Saitoh A novel antagonist, phenylbenzene ω-phosphono-α-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br.J.Pharmacol. 1994 PMID: 7812607
Schmeiden and Betz Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 1995 PMID: 7476923

Citations (1)

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Citations are publications that use Bio-Techne products. Selected citations for L-Serine include:

Potier et al. (2010) Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci. 2:1
PMID: 20552041

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Product Datasheets

COA

Certificate of Analysis

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L-Serine

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Key Product Details

Biological Activity

Technical Data

Solubility

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References

Citations (1)

Product Datasheets

COA

Certificate of Analysis

SDS

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