L-(-)-α-Methyldopa

Name: L-(-)- α -Methyldopa
Brand: Tocris Bioscience
SKU: 0584

Tocris Bioscience a Bio-Techne Brand

Catalog # 0584

COA / SDS

Discontinued Product

0584 has been discontinued. View all Decarboxylase Inhibitors products.

Key Product Details

Description:	Aromatic L-amino acid decarboxylase inhibitor
Chemical Name:	3-(3,4-Dihydroxyphenyl)-α-methyl-L-alanine
Molecular Weight:	211.22

View Full Technical Details for L-(-)-α-Methyldopa

Biological Activity for L-(-)-α-Methyldopa

L-(-)-α-Methyldopa is a L-aromatic amino acid decarboxylase inhibitor. Antihypertensive.

Technical Data for L-(-)-α-Methyldopa

M. Wt	211.22
Formula	C₁₀H₁₃NO₄
Storage	Store at RT
CAS Number	555-30-6
PubChem ID	38853
InChi Key	CJCSPKMFHVPWAR-JTQLQIEISA-N
Smiles	OC1=C(O)C=C(C[C@@](N)(C)C(O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for L-(-)-α-Methyldopa

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	15.84	75

Preparing Stock Solutions for L-(-)-α-Methyldopa

The following data is based on the product molecular weight 211.22.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.75 mM	6.31 mL	31.56 mL	63.13 mL
3.75 mM	1.26 mL	6.31 mL	12.63 mL
7.5 mM	0.63 mL	3.16 mL	6.31 mL
37.5 mM	0.13 mL	0.63 mL	1.26 mL

Molarity Calculator

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Reconstitution Calculator

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References for L-(-)-α-Methyldopa

References are publications that support the biological activity of the product.

Kapoor and Chalmers Correlation between fall in blood pressure and in vivo amine release after α-methylDOPA. Eur.J.Pharmacol. 1989 PMID: 2767124
Van Zwieten The hypotensive activity and side effects of methyldopa, clonidine, and guanf. Hypertension 1984 PMID: 6094346

Citations for L-(-)-α-Methyldopa

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