L-693,403 maleate

Name: L-693,403 maleate
Brand: Tocris Bioscience
SKU: 0426

Tocris Bioscience a Bio-Techne Brand

Catalog # 0426

COA / SDS

Discontinued Product

0426 has been discontinued. View all General Sigma Receptor Ligands products.

Key Product Details

Description:	High affinity σ ligand
Chemical Name:	N-1'-Benzyl-3,4-dihydrospiro[1H-indene-1,4'-piperidine] maleate
Molecular Weight:	393.48

View Full Technical Details for L-693,403 maleate

Biological Activity for L-693,403 maleate

L-693,403 maleate is a high affinity σ ligand with excellent selectivity over the dopamine D₂ receptor.

Licensing Information

Sold with the permission of Merck Sharp and Dohme Ltd.

Technical Data for L-693,403 maleate

M. Wt	393.48
Formula	C₂₀H₂₃N.C₄H₄O₄
Storage	Desiccate at -20°C
CAS Number	207455-21-8
PubChem ID	56972153
InChi Key	WAZQVIBRRAMDNX-BTJKTKAUSA-N
Smiles	OC(=O)\C=C/C(O)=O.C(N1CCC2(CCC3=C2C=CC=C3)CC1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for L-693,403 maleate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	39.35	100

Preparing Stock Solutions for L-693,403 maleate

The following data is based on the product molecular weight 393.48.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.54 mL	12.71 mL	25.41 mL
5 mM	0.51 mL	2.54 mL	5.08 mL
10 mM	0.25 mL	1.27 mL	2.54 mL
50 mM	0.05 mL	0.25 mL	0.51 mL

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Reconstitution Calculator

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References for L-693,403 maleate

References are publications that support the biological activity of the product.

Chambers Spiropiperidines as high affinity selective sigma ligands. J.Med.Chem. 1992 PMID: 1317923

Citations for L-693,403 maleate

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Product Documents for L-693,403 maleate

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.