Ketotifen fumarate

Name: Ketotifen fumarate
Brand: Tocris Bioscience
SKU: 0784

Catalog # 0784

COA / SDS

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Bio-Techne Corporation

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$35 to United States

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Key Product Details

Description:	H₁ antagonist
Chemical Name:	4,9-Dihydro-4-(1-methyl-4-piperidinylidene-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate
Purity:	≥99% (HPLC)
Molecular Weight:	425.5

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Biological Activity

Ketotifen fumarate is an an H₁ receptor antagonist.

Technical Data

M. Wt	425.5
Formula	C₁₉H₁₉NOS.C₄H₄O₄
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	34580-14-8
PubChem ID	5282408
InChi Key	YNQQEYBLVYAWNX-WLHGVMLRSA-N
Smiles	OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=C1C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	42.55	100

Preparing Stock Solutions

The following data is based on the product molecular weight 425.5.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.35 mL	11.75 mL	23.50 mL
5 mM	0.47 mL	2.35 mL	4.70 mL
10 mM	0.24 mL	1.18 mL	2.35 mL
50 mM	0.05 mL	0.24 mL	0.47 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Abu-Dalu The actions of ketotifen on intestinal smooth muscles. Eur.J.Pharmacol. 1996 PMID: 8874138
Martin and Römer The pharmacological properties of a new orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene. Arzneimittelforschung 1978 PMID: 35171

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