ICI 89406

Name: ICI 89406
Brand: tocris
SKU: 0832

Catalog # 0832

Citations (2)

Datasheet / COA / SDS

Discontinued Product

0832 has been discontinued. View all Non-selective Adrenergic beta Receptor Antagonists products.

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$35 to United States

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Key Product Details

Description:	β antagonist
Chemical Name:	N-[2-[3-(2-Cyanophenoxy)-2-hydroxypropylamino]ethyl]-N'-phenylurea
Purity:	≥99% (HPLC)
Molecular Weight:	354.41

View Full Technical Details for ICI 89406

Technical Data
Citations (2) / Reviews

Biological Activity

β-adrenergic antagonist and low efficacy partial agonist; does not affect resting cardiac parameters.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M. Wt	354.41
Formula	C₁₉H₂₂N₄O₃
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	53671-71-9
PubChem ID	123686
InChi Key	HTLWRKRZKFAAAH-UHFFFAOYSA-N
Smiles	OC(CNCCNC(=O)NC1=CC=CC=C1)COC1=C(C=CC=C1)C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

Soluble in ethanol and to 100 mM in DMSO

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References

References are publications that support the biological activity of the product.

Mai β-Adrenergic Receptors. Comprehensive Medicinal Chemistry. Ed. Hansch.

Citations (2)

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Citations are publications that use Bio-Techne products. Selected citations for ICI 89406 include:

Mistry et al. (2013) Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. J Med Chem. 56:3852
PMID: 23614528
Kaya et al. (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. J Pharmacol Exp Ther. 329:350
PMID: 19144685

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Product Datasheets

COA

Certificate of Analysis

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ICI 89406

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Key Product Details

Biological Activity

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Technical Data

Solubility

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References

Citations (2)

Product Datasheets

COA

Certificate of Analysis

SDS

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