ICI 162,846

Name: ICI 162,846
Brand: tocris
SKU: 0833

Catalog # 0833

Datasheet / COA / SDS

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Key Product Details

Description:	Potent H₂ antagonist, active in vivo
Chemical Name:	N-[1-(4-Carboxamidobutyl)-1H-pyrazol-3-yl)]-N'-(2,2,2-trifluoroethyl)guanidine
Molecular Weight:	306.29

View Full Technical Details for ICI 162,846

Biological Activity

A potent histamine H₂ receptor antagonist.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M. Wt	306.29
Formula	C₁₁H₁₇F₃N₆O
Storage	Store at RT
CAS Number	84545-30-2
PubChem ID	134778
InChi Key	ALCSGJCIESECFD-UHFFFAOYSA-N
Smiles	NC(=O)CCCCN1C=CC(=N1)\N=C(/N)NCC(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References

References are publications that support the biological activity of the product.

Gompertz Acid blockade by omeprazole or ICI 162846 in a chronic duodenal ulcer model. Agents Actions 1991 PMID: 1716826
Streett Morphological stomach findings in rats and mice treated with the H₂ receptor antagonists, ICI 125,211 and ICI 162,846. Toxicol.Pathol. 1988 PMID: 2903545
Wilson Inhibition of human gastric secretion by ICI 162,846 - a new histamine H₂ receptor antagonist. Br.J.Clin.Pharmacol. 1986 PMID: 2874823

Citations

Currently there are no citations for ICI 162,846.

Product Datasheets

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