ICI 154,129

Name: ICI 154,129
Brand: Tocris Bioscience
SKU: 0827

Catalog # 0827

Citations (1)

COA / SDS

Discontinued Product

0827 has been discontinued. View all delta Opioid Receptor Antagonists products.

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Bio-Techne Corporation

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$35 to United States

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Key Product Details

Description:	δ selective peptide antagonist
Molecular Weight:	638.83

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Biological Activity

ICI 154,129 is a selective δ opioid antagonist.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M. Wt	638.83
Formula	C₃₄H₄₆N₄O₆S
Single Letter Sequence	YGFL (Modifications: Tyr-1 = N,N-diallyl-Tyr, Gly-2 - Phe-3 peptide bond replaced with Psi-(CH₂S))
Storage	Desiccate at -20°C
CAS Number	83420-94-4
PubChem ID	3035055
InChi Key	CZRZYRKTYLLLRL-DTXPUJKBSA-N
Smiles	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)SCCNC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)N(CC=C)CC=C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

Soluble to 1mg/ml in methanol

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References

References are publications that support the biological activity of the product.

Rees and Hunter Opioid Receptors. Comprehensive Medicinal Chemistry. Ed. Hansch.
Shaw Selective antagonists at the opiate delta-receptor. Life Sci. 1982 PMID: 6128652

Citations for ICI 154,129 (1)

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Citations are publications that use Bio-Techne products. Selected citations for ICI 154,129 include:

Jiang et al. (2015) Analgesic roles of peripheral intrinsic met-enkephalin and dynorphin A in long-lasting inflammatory pain induced by complete Freund's adjuvant in rats. J Pharmacol Exp Ther. 9:2344
PMID: 26136984

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