Hemopressin (rat)

Name: Hemopressin (rat)
Brand: Tocris Bioscience
SKU: 1764

Tocris Bioscience a Bio-Techne Brand

Catalog # 1764

COA / SDS

Discontinued Product

1764 has been discontinued. View all Cannabinoid R1 / CB1 Inverse Agonists products.

Key Product Details

Description:	Selective CB₁ inverse agonist
Molecular Weight:	1088.27

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Biological Activity for Hemopressin (rat)

Hemopressin (rat) is a bioactive endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE. K_i values are 27.76, 3.43 and 1.87 μM respectively. Potent hypotensive in vivo. Also acts as a selective CB₁ receptor inverse agonist. Displays antinociceptive activity and induces hypophagia in vivo.

Technical Data for Hemopressin (rat)

M. Wt	1088.27
Formula	C₅₃H₇₇N₁₃O₁₂
Single Letter Sequence	PVNFKFLSH
Storage	Desiccate at -20°C
CAS Number	568588-77-2
PubChem ID	44560117
InChi Key	DUTLYPZZJJBEAJ-QISMNGAHSA-N
Smiles	[H]N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Hemopressin (rat)

References are publications that support the biological activity of the product.

Todd The peptide hemopressin acts through CB₁ cannabinoid receptors to reduce food intake in rats and mice. J.Neurosci. 2010 PMID: 20505104
Heimann Hemopressin is an inverse agonist of CB₁ cannabinoid receptors. Proc.Natl.Acad.Sci.U.S.A. 2007 PMID: 18077343
Rioli Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme. J.Biol.Chem. 2003 PMID: 12500972

Citations for Hemopressin (rat)

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Hemopressin (rat)

Tocris Bioscience a Bio-Techne Brand

Key Product Details

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Biological Activity for Hemopressin (rat)

Technical Data for Hemopressin (rat)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Hemopressin (rat)

Citations for Hemopressin (rat)

Product Documents for Hemopressin (rat)

COA

Certificate of Analysis

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