FPL 55712

Name: FPL 55712
Brand: Tocris Bioscience
SKU: 2276

Tocris Bioscience a Bio-Techne Brand

Catalog # 2276

Citations (1)

COA / SDS

Discontinued Product

2276 has been discontinued. View all Leukotriene and Related Receptor Antagonists products.

Key Product Details

Description:	Leukotriene receptor antagonist
Chemical Name:	7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid
Purity:	≥97% (HPLC)
Molecular Weight:	498.52

View Full Technical Details for FPL 55712

Biological Activity for FPL 55712

FPL 55712 is a leukotriene receptor antagonist; inhibits contraction of guinea pig trachealis induced by leukotrienes C₄, D₄, E₄ and F₄.

Technical Data for FPL 55712

M. Wt	498.52
Formula	C₂₇H₃₀O₉
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	40785-97-5
PubChem ID	105007
InChi Key	LMQBMWHHGVZWMR-UHFFFAOYSA-N
Smiles	CCCC1=C(O)C(=CC=C1OCC(O)COC1=CC=C2C(=O)C=C(OC2=C1CCC)C(O)=O)C(C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for FPL 55712

References are publications that support the biological activity of the product.

Folkerts Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. Eur.J.Pharmacol. 1995 PMID: 8566126
O'Donnell and Welto Pharmacologic properties of FPL 55712 administered by aerosol. Agents Actions 1984 PMID: 6322547
Jones Pharmacological study of the effects of leukotrienes C4, D4, E4 & F4 on guinea pig trachealis: interaction with FPL-55712. Prostaglandins 1983 PMID: 6322240

Citations for FPL 55712 (1)

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Citations are publications that use Bio-Techne products. Selected citations for FPL 55712 include:

Wright et al. (2019) Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2. Biochem Biophys Res Commun. 520:35
PMID: 31564414

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Product Documents for FPL 55712

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.