D-Glutamic acid

Name: D-Glutamic acid
Brand: tocris
SKU: 0217

Catalog # 0217

Datasheet / COA / SDS

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Key Product Details

Description:	Endogenous, non-selective agonist. Less active enantiomer
Chemical Name:	(R)-1-Aminopropane-1,3-dicarboxylic acid
Molecular Weight:	147.13

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Biological Activity

Excitatory amino acid acting at NMDA receptors; less active than the L-isomer.

L-isomer also available.

Technical Data

M. Wt	147.13
Formula	C₅H₉NO₄
Storage	Store at RT
CAS Number	6893-26-1
PubChem ID	23327
InChi Key	WHUUTDBJXJRKMK-GSVOUGTGSA-N
Smiles	N[C@@]([H])([C@](O)=O)CCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	1eq. NaOH		100

Preparing Stock Solutions

The following data is based on the product molecular weight 147.13.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	6.80 mL	33.98 mL	67.97 mL
5 mM	1.36 mL	6.80 mL	13.59 mL
10 mM	0.68 mL	3.40 mL	6.80 mL
50 mM	0.14 mL	0.68 mL	1.36 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Olverman Structure/activity relations of N-MthD.-aspartate receptor ligands as studied by their inhibition of [³H]-D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience 1988 PMID: 2901691
Watkins Twenty five years of excitatory amino acid research. Excitatory Amino Acids. Eds. Roberts et al. Macmil