Cimaterol

Name: Cimaterol
Brand: Tocris Bioscience
SKU: 0435

Tocris Bioscience a Bio-Techne Brand

Catalog # 0435

Citations (2)

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Key Product Details

Description:	β agonist
Chemical Name:	2-Amino-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]benzonitrile
Purity:	≥99% (HPLC)
Molecular Weight:	219.29

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Biological Activity for Cimaterol

Cimaterol is a β-Adrenergic agonist.

Technical Data for Cimaterol

M. Wt	219.29
Formula	C₁₂H₁₇N₃O
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	54239-37-1
PubChem ID	2755
InChi Key	BUXRLJCGHZZYNE-UHFFFAOYSA-N
Smiles	CC(C)NCC(O)C1=CC=C(N)C(=C1)C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Cimaterol

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	ethanol	21.93	100
	DMSO	21.93	100

Preparing Stock Solutions for Cimaterol

The following data is based on the product molecular weight 219.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.56 mL	22.80 mL	45.60 mL
5 mM	0.91 mL	4.56 mL	9.12 mL
10 mM	0.46 mL	2.28 mL	4.56 mL
50 mM	0.09 mL	0.46 mL	0.91 mL

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Reconstitution Calculator

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References for Cimaterol

References are publications that support the biological activity of the product.

Strosberg and Pietri-Rouxel Function and regulation of the β₃-adrenoceptor. TiPS 1996 PMID: 8979772
Lafontan Mechanisms of actions of β-adrenergic agonists - lipomobilization and anabolism. Reprod.Nutr.Develop.
Engelhardt Structure activity relationships in further series of amino-halogen substituted phenyl-aminoethanols. Arzneimittelforschung 1984 PMID: 6152155

Citations for Cimaterol (2)

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Citations are publications that use Bio-Techne products. Selected citations for Cimaterol include:

Mistry et al. (2013) Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. J Med Chem. 56:3852
PMID: 23614528
Kaya et al. (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. J Pharmacol Exp Ther. 329:350
PMID: 19144685

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