Carbetapentane citrate

Name: Carbetapentane citrate
Brand: tocris
SKU: 0454

Catalog # 0454

Citations (1)

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Key Product Details

Description:	High affinity σ₁ ligand
Alternative Names:	Pentoxyverine citrate
Chemical Name:	1-Phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethoxy)ethyl ester citrate
Purity:	≥99% (HPLC)
Molecular Weight:	525.59

View Full Technical Details for Carbetapentane citrate

Biological Activity

A selective ligand for the σ₁ -site.

Technical Data

M. Wt	525.59
Formula	C₂₀H₃₁NO₃.C₆H₈O₇
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	23142-01-0
PubChem ID	90010
InChi Key	AKJDEXBCRLOVTH-UHFFFAOYSA-N
Smiles	OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)CCOCCOC(=O)C1(CCCC1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	39.42	75

Preparing Stock Solutions

The following data is based on the product molecular weight 525.59.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.75 mM	2.54 mL	12.68 mL	25.37 mL
3.75 mM	0.51 mL	2.54 mL	5.07 mL
7.5 mM	0.25 mL	1.27 mL	2.54 mL
37.5 mM	0.05 mL	0.25 mL	0.51 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Quirion A proposal for the classification of sigma binding sites. TiPS 1992 PMID: 1315463
Rothman Labelling by [³H]1,3-di(2-tolyl)guanidine of two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by σ ligands. Mol.Pharmacol. 1991 PMID: 1847495

Citations (1)

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Citations are publications that use Bio-Techne products. Selected citations for Carbetapentane citrate include:

Shin et al. (2006) Vasoconstrictive neurovascular coupling during focal ischemic depolarizations. J Cereb Blood Flow Metab. 26:1018
PMID: 16340958

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Product Datasheets

COA

Certificate of Analysis

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Carbetapentane citrate

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References

Citations (1)

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