BP 554 maleate

Name: BP 554 maleate
Brand: tocris
SKU: 0556

Catalog # 0556

Citations (2)

Datasheet / COA / SDS

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Key Product Details

Description:	Selective 5-HT_1A agonist
Chemical Name:	1-[3-(3,4-Methylenedioxyphenoxy)propyl]-4-phenyl-piperazine maleate
Purity:	≥99% (HPLC)
Molecular Weight:	456.48

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Biological Activity

Selective 5-HT_1A agonist.

Technical Data

M. Wt	456.48
Formula	C₂₀H₂₄N₂O₃.C₄H₄O₄
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	1221401-95-1
PubChem ID	56972150
InChi Key	NBCXNOHQTALBRA-BTJKTKAUSA-N
Smiles	OC(=O)\C=C/C(O)=O.C(COC1=CC=C2OCOC2=C1)CN1CCN(CC1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	45.65	100

Preparing Stock Solutions

The following data is based on the product molecular weight 456.48.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.19 mL	10.95 mL	21.91 mL
5 mM	0.44 mL	2.19 mL	4.38 mL
10 mM	0.22 mL	1.10 mL	2.19 mL
50 mM	0.04 mL	0.22 mL	0.44 mL

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References

References are publications that support the biological activity of the product.

Matsuda Agonist activity of a novel compound, 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenyl piperazine (BP-554) at central 5-HT_1A receptors. Eur.J.Pharmacol. 1989 PMID: 2533078

Citations (2)

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Citations are publications that use Bio-Techne products. Selected citations for BP 554 maleate include:

Akoume et al. (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep. 9:10074
PMID: 31296888
Huang et al. (2009) Autocrine and paracrine roles for ATP and serotonin in mouse taste buds. Br J Pharmacol. 29:13909
PMID: 19890001

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Product Datasheets

COA

Certificate of Analysis

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BP 554 maleate

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References

Citations (2)

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