Acamprosate calcium

Name: Acamprosate calcium
Brand: Tocris Bioscience
SKU: 3618

Catalog # 3618 | Tocris Bioscience a Bio-Techne Brand

COA / SDS

GABA agonist; also glutamatergic modulator

Discontinued Product

3618 has been discontinued. View all GABA-A Receptor Agonists products.

Key Product Details

Description:	GABA agonist; also glutamatergic modulator
Alternative Names:	Calcium acetylhomotaurinate
Chemical Name:	3-(Acetylamino)-1-propanesulfonic acid hemicalcium salt
Molecular Weight:	200.24

View Full Technical Details for Acamprosate calcium

Technical Data
Citations / Reviews

Biological Activity for Acamprosate calcium

Acamprosate calcium is a GABA receptor agonist and modulator of glutamatergic systems. Reduces alcohol consumption in animal models of alcohol addiction.

Technical Data for Acamprosate calcium

M. Wt	200.24
Formula	C₅H₁₀NO₄S.½ Ca
Storage	Desiccate at RT
CAS Number	77337-73-6
PubChem ID	155434
InChi Key	BUVGWDNTAWHSKI-UHFFFAOYSA-L
Smiles	CC(=O)NCCCS(=O)(=O)[O-].CC(=O)NCCCS(=O)(=O)[O-].[Ca+2]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Acamprosate calcium

References are publications that support the biological activity of the product.

Popp and Lovinger Interaction of acampr. with ethanol and spermine on NMDA receptors in primary cultured neurons. Eur.J.Pharmacol. 2000 PMID: 10771287
Berton Acamprosate enhances N-MthD.-aspartate receptor-mediated neurotransmission but inhibits presynaptic GABA(B) receptors in nucleus accumbens neurons. Alcohol Clin.Exp.Res. 1998 PMID: 9514305
Spanagel Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat. Eur.J.Pharmacol. 1996 PMID: 8813529

Citations for Acamprosate calcium

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