2R,6R-Hydroxynorketamine hydrochloride
Catalog # 6094 | Tocris Bioscience a Bio-Techne Brand
Enhances AMPA currents; decreases D-serine (a NMDA co-agonist); lacks ketamine-related side effects
Loading...
Key Product Details
Description: | Enhances AMPA currents; decreases D-serine (a NMDA co-agonist); lacks ketamine-related side effects |
Chemical Name: | (2R,6R)-2-Amino-2-(2-chlorophenyl)-6-hydroxycyclohexanone hydrochloride |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 276.16 |
Citations for 2R,6R-Hydroxynorketamine hydrochloride (10)
Showing
1
-
10 of
10 citations
Showing All
Search Title:
Citations are publications that use Bio-Techne products. Selected citations for 2R,6R-Hydroxynorketamine hydrochloride include:
-
Plinio C et al.
(2023)
Ketamine and its metabolite 2R,6R-hydroxynorketamine promote ocular dominance plasticity and release tropomyosin-related kinase B from inhibitory control without reducing perineuronal nets enwrapping parvalbumin interneurons.
Eur J Neurosci.
57:940-950
PMID: 36740723 -
Eero et al.
(2023)
TRKB interaction with PSD95 is associated with latency of fluoxetine and 2R,6R-hydroxynorketamine.
Eur J Neurosci.
57:1215-1224
PMID: 36876503 -
Tomasz et al.
(2023)
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB.
Nat Neurosci.
26:1032-1041
PMID: 37280397 -
Eero et al.
(2022)
Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro.
Front Pharmacol.
12:755600
PMID: 35126106 -
Jian-Hua et al.
(2020)
The Ventrolateral Periaqueductal Gray Contributes to Depressive-Like Behaviors in Recovery of Inflammatory Bowel Disease Rat Model.
Front Neurosci.
14:254
PMID: 32265648 -
Xiangmin et al.
(2020)
Subanesthetic Ketamine Reactivates Adult Cortical Plasticity to Restore Vision from Amblyopia.
Curr Biol.
30:3591-3603.e8
PMID: 32822611 -
Ye et al.
(2019)
KA metabolite (2R,6R)-hydroxynorKA enhances aggression via periaqueductal gray glutamatergic transmission.
Neuropharmacology.
157
PMID: 31207251 -
Ago et al.
(2019)
(R)-Ketamine induces a greater increase in prefrontal 5-HT release than (S)-Ketamine and Ketamine Metabolites via an AMPA receptor-independent mechanism.
Int J Neuropsychopharmacol.
22:665
PMID: 31325908 -
Eero et al.
(2019)
Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2.
J Biol Chem.
294:18150-18161
PMID: 31631060 -
Chou et al.
(2018)
(2R,6R)-hydroxynorKA rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray.
Neuropharmacology.
139:1
PMID: 29953886
There are no citations that match your criteria.