2-MPMDQ

Tocris Bioscience a Bio-Techne Brand

Catalog # 0661

COA / SDS

Discontinued Product

0661 has been discontinued. View all Adrenergic alpha-1 Receptor Antagonists products.

Key Product Details

Description:	Potent, selective α₁ antagonist. Also σ₂ ligand
Chemical Name:	2-[[4-(2-Methoxyphenyl)piperazin-1-yl]methyl-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one
Molecular Weight:	405.5

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Biological Activity for 2-MPMDQ

2-MPMDQ is a potent and selective α₁-adrenoceptor antagonist; hypotensive.

Technical Data for 2-MPMDQ

M. Wt	405.5
Formula	C₂₃H₂₇N₅O₂
Storage	Store at RT
CAS Number	149847-77-8
PubChem ID	4534085
InChi Key	OULFYKAESNCMFJ-UHFFFAOYSA-N
Smiles	COC1=C(C=CC=C1)N1CCN(CC2CN3C(=N2)C2=CC=CC=C2N(C)C3=O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 2-MPMDQ

Solubility

Soluble Soluble to 50 mM in DMSO

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References for 2-MPMDQ

References are publications that support the biological activity of the product.

Chern Studies on quinazolines. 2,3-Dihydroimidazo[1,2c]quinazoline derivatives. A novel class of potent and selective α₁-adrenoceptor antagonists and antihypertensive agents. J.Med.Chem. 1993 PMID: 8101878

Citations for 2-MPMDQ

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Product Documents for 2-MPMDQ

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.