2-MPMDQ

Catalog # 0661

Datasheet / COA / SDS

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Key Product Details

Description:	Potent, selective α₁ antagonist. Also σ₂ ligand
Chemical Name:	2-[[4-(2-Methoxyphenyl)piperazin-1-yl]methyl-6-methyl-2,3-dihydroimidazo[1,2c]quinazolin-5(6H)-one
Molecular Weight:	405.5

View Full Technical Details for 2-MPMDQ

Biological Activity

2-MPMDQ is a potent and selective α₁-adrenoceptor antagonist; hypotensive.

Technical Data

M. Wt	405.5
Formula	C₂₃H₂₇N₅O₂
Storage	Store at RT
CAS Number	149847-77-8
PubChem ID	4534085
InChi Key	OULFYKAESNCMFJ-UHFFFAOYSA-N
Smiles	COC1=C(C=CC=C1)N1CCN(CC2CN3C(=N2)C2=CC=CC=C2N(C)C3=O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	20.27	50

Preparing Stock Solutions

The following data is based on the product molecular weight 405.5.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	4.93 mL	24.66 mL	49.32 mL
2.5 mM	0.99 mL	4.93 mL	9.86 mL
5 mM	0.49 mL	2.47 mL	4.93 mL
25 mM	0.10 mL	0.49 mL	0.99 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Chern Studies on quinazolines. 2,3-Dihydroimidazo[1,2c]quinazoline derivatives. A novel class of potent and selective α₁-adrenoceptor antagonists and antihypertensive agents. J.Med.Chem. 1993 PMID: 8101878

Citations

Currently there are no citations for 2-MPMDQ.

Product Datasheets

COA

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service.