Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Neutralization

Label

Janelia Fluor 549

Antibody Source

Monoclonal Mouse IgG2A Clone # 563418

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SMPD1 Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human SMPD1 isoform 1
His62-Pro628
Accession # NP_000534

Specificity

Detects human SMPD1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human SMPD3 and recombinant mouse SMPD1 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for SMPD1 Antibody (563418) [Janelia Fluor® 549]

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: SMPD1

The protein encoded by the SMPD1 gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Three transcript variants encoding two different isoforms have been found for this gene. (provided by RefSeq)

Long Name

Sphingomyelin Phosphodiesterase 1, Acid Lysosomal

Alternate Names

aSMase, NPD

Gene Symbol

SMPD1

Additional SMPD1 Products

Product Documents for SMPD1 Antibody (563418) [Janelia Fluor® 549]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SMPD1 Antibody (563418) [Janelia Fluor® 549]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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