Human EGFR Antibody
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity: | Human |
Immunogen: |
Mouse myeloma cell line NS0-derived recombinant human EGFR Leu25-Ser645 Accession # CAA25240 |
Applications: | CyTOF-ready, ELISA Capture, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Simple Western, Western Blot |
Label: | Unconjugated |
Source: | Polyclonal Goat IgG |
Specificity: |
Detects human EGFR in ELISAs and Western blots. In sandwich ELISAs, approximately 3% cross-reactivity with recombinant mouse EGFR is observed and less than 0.1% cross-reactivity with recombinant human (rh) ErbB2 and rhErbB3 is observed. |
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Citations for Human EGFR Antibody (15)
Citations are publications that use Bio-Techne products. Selected citations for Human EGFR Antibody include:
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Species: Human
Sample Types: Cell Lysates
Applications: Western BlotC Hu et al. (2022), Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias Nature, 602(7897):518-522.
PMID: 35140400 -
Species: Human
Sample Types: Cell Lysates
Applications: ImmunoprecipitationDM Beauvais et al. (2022), Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression The Journal of Biological Chemistry, 0(0):102029.
PMID: 35569509 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCS Sugita et al. (2021), Involvement of cancer-derived EMT cells in the accumulation of 18F-fluorodeoxyglucose in the hypoxic cancer microenvironment Scientific Reports, 11(1):9668.
PMID: 33994540 -
Species: Human
Sample Types: Cell Lysates
Applications: Co-ImmunoprecipitationX Liu et al. (2021), EGFR inhibition blocks cancer stem cell clustering and lung metastasis of triple negative breast cancer Theranostics, 11(13):6632-6643.
PMID: 33995681 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotR Chakrabort et al. (2021), Bacterial Antigens Reduced the Inhibition Effect of Capsaicin on Cal 27 Oral Cancer Cell Proliferation International Journal of Molecular Sciences, 22(16).
PMID: 34445392 -
Species: Human
Sample Types: Whole Cell
Applications: IFT Egnuni et al. (2021), Evaluation of the Targeting and Therapeutic Efficiency of Anti-EGFR Functionalised Nanoparticles in Head and Neck Cancer Cells for Use in NIR-II Optical Window Pharmaceutics, 13(10).
PMID: 34683944 -
Species: Human
Sample Types: Cell Lysates
Applications: ELISA DetectionN Yogo et al. (2020), Development of an immuno-wall device for the rapid and sensitive detection of EGFR mutations in tumor tissues resected from lung cancer patients PLoS ONE, 15(11):e0241422.
PMID: 33196648 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PA Klaesson et al. (2018), Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes Sci Rep, 8(1):5400.
PMID: 29599435 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotF Haun et al. (2018), Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin Nat Commun, 9(1):3524.
PMID: 30166526 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PSuzanne D Burke (2016), Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia J Clin Invest, 0(0).
PMID: 27270170 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotNanjo et al. (2013), Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors. PLoS ONE, 8(12):e84700.
PMID: 24386407 -
Species: Human
Sample Types: Cell Lysates
Applications: ELISA DevelopmentSarup J et al. (2008), Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts. Mol. Cancer Ther., 7(10):3223-36.
PMID: 18852126 -
Species: Human
Sample Types: Serum
Applications: ELISA Microarray DevelopmentGonzalez RM et al. (2008), Development and validation of sandwich ELISA microarrays with minimal assay interference. J. Proteome Res., 7(6):2406-14.
PMID: 18422355 -
Species: Human
Sample Types: Cell Lysates
Applications: ImmunoprecipitationKunii K et al. (2008), FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival. Cancer Res., 68(7):2340-8.
PMID: 18381441 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCMurphy MO et al. (2006), Expression of growth factors and growth factor receptor in non-healing and healing ischaemic ulceration. Eur J Vasc Endovasc Surg, 31(5):516-22.
PMID: 16427789
There are no citations that match your criteria.
Customer Reviews for Human EGFR Antibody (1)
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Application: WBSample Tested: HT-29 human colon adenocarcinoma cell lineSpecies: HumanVerified Customer | Posted 07/31/2018
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