HSP90 Antibody (4F3.E8) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12878PE

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP2-12878AF350

Alexa Fluor 405

NBP2-12878AF405

Alexa Fluor 488

NBP2-12878AF488

Alexa Fluor 532

NBP2-12878AF532

Alexa Fluor 594

NBP2-12878AF594

Alexa Fluor 647

NBP2-12878AF647

Alexa Fluor 700

NBP2-12878AF700

Alexa Fluor 750

NBP2-12878AF750

Allophycocyanin

NBP2-12878APC

Biotin

NBP2-12878B

CoraFluor 1

NBP2-12878CL1

DyLight 350

NBP2-12878UV

DyLight 405

NBP2-12878V

DyLight 488

NBP2-12878G

DyLight 550

NBP2-12878R

DyLight 594

NBP2-12878DL594

DyLight 650

NBP2-12878C

DyLight 680

NBP2-12878FR

DyLight 755

NBP2-12878IR

FITC

NBP2-12878F

HRP

NBP2-12878H

Janelia Fluor 525

NBP2-12878JF525

Janelia Fluor 549

NBP2-12878JF549

Janelia Fluor 646

NBP2-12878JF646

Janelia Fluor 669

NBP2-12878JF669

mFluor Violet 450 SE

NBP2-12878MFV450

mFluor Violet 500 SE

NBP2-12878MFV500

mFluor Violet 610 SE

NBP2-12878MFV610

PerCP

NBP2-12878PCP

Forumulation

Catalog #

BSA Free

NBP2-12878

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat, Plant

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Electron Microscopy

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Mouse IgG_2A Clone # 4F3.E8

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HSP90 Antibodies »

Product Specifications

Immunogen

Recombinant Human HSP90 purified from E.coli

Reactivity Notes

Immunogen displays sequence identity for non-tested species: Wheat (Triticum spp).

Localization

Cytoplasm , Melanosome

Specificity

Detects approx 90kDa. This antibody detects both a and B forms of HSP90 equally well.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Theoretical MW

90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications for HSP90 Antibody (4F3.E8) [PE]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Electron Microscopy

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: HSP90

Hsp90 has at least 2 isoforms, Hsp90a and Hsp90b which are encoded by separate genes. These ubiquitous and highly conserved proteins account for 1-2% of all cellular proteins in most cells. Hsp90 is part of the cells powerful network of chaperones to fight the deleterious consequences of protein unfolding caused by nonphysiological conditions. However, in the absence of stress, Hsp90 is a necessary component of fundamental cellular processes such as hormone signaling and cell cycle control. In this context several key regulatory proteins such as steroid receptors, cell cycle kinases involved in signal transduction and p53 have been identified as substrates of Hsp90. It has been suggested that Hsp90 acts as a capacitor for morphological evolution by buffering widespread variation, which may affect morphogenic pathways.

Long Name

Heat Shock Protein 90

Alternate Names

FLJ31884, Heat shock 86 kDa, heat shock 90kD protein 1, alpha, heat shock 90kD protein 1, alpha-like 4, heat shock 90kD protein, alpha-like 4, heat shock 90kDa protein 1, alpha, heat shock protein 90kDa alpha (cytosolic), class A member 1, heat shock protein HSP 90-alpha, Hsp89, Hsp90, HSP90AHSP86, HSP90N, HSPC1HSP 86, HSPCAHSP89A, HSPCAL1, HSPCAL4, HSPN, LAP2, Renal carcinoma antigen NY-REN-38

Gene Symbol

HSP90AA1

Additional HSP90 Products

Product Documents for HSP90 Antibody (4F3.E8) [PE]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for HSP90 Antibody (4F3.E8) [PE]

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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