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Clostridium Botulinum Toxin A Antibody, Novus Biologicals

Bio-Techne includes Novus Biologicals | Catalog # NB110-17098

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NB110-17098

Key Product Details

Species Reactivity

Validated:

Bacteria

Applications

Dot Blot, ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Clostridium Botulinum Toxin A Antibody

Immunogen

Type A Neurotoxin

Reactivity Notes

C. botulinum Type A Neurotoxin

Localization

Secreted

Specificity

Clostridium botulinum Type A Neurotoxin.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

149 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications for Clostridium Botulinum Toxin A Antibody

Application
Recommended Usage

Dot Blot

1:100-1:2000

ELISA

1:10000

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

1X PBS (pH 7.2) containing 20% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Clostridium Botulinum Toxin A

Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.

Alternate Names

Atx, Bna, BoNT/A, Bontoxilysin A, BotA, BOTOX, Botulinum neurotoxin type A, Botulism A toxoid

Additional Clostridium Botulinum Toxin A Products

Product Documents for Clostridium Botulinum Toxin A Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Clostridium Botulinum Toxin A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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