APBB2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48131

Novus Biologicals, part of Bio-Techne
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NBP3-48131
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all APBB2 Antibodies »

Product Specifications

Immunogen

amyloid beta(A4) precursor protein-binding, family B, member 2. (Uniprot# Q92870)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for APBB2 Antibody - BSA Free

APBB2 Antibody - BSA Free

Western Blot: APBB2 Antibody - BSA Free [NBP3-48131] -

Western Blot: APBB2 Antibody - BSA Free [NBP3-48131] - Human brain tissue were subjected to SDS PAGE followed by western blot with (APBB2 antibody) at dilution of 1:300

Applications for APBB2 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000
Application Notes
Theoretical Molecular Weight is 83-95 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: APBB2

Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the beta-Amyloid and Amyloid A4 proteins, which are present in human platelets. Amyloid deposition is associated with type II diabetes, Down's syndrome and a variety of neurological disorders, including Alzheimer's disease. The Amyloid precursor protein (APP) undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the 4 kDa Amyloid ®/A4 protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane- bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients.

Alternate Names

amyloid beta (A4) precursor protein-binding, family B, member 2, amyloid beta A4 precursor protein-binding family B member 2, DKFZp434E033, FE65L1FE65LMGC35575, Fe65-like 1, Protein Fe65-like 1

Gene Symbol

APBB2

Additional APBB2 Products

Product Documents for APBB2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for APBB2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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