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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Summary for ABC2 Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 250 and 300 of human amplified in breast cancer gene 2 protein using the numbering given in entry NP_060619.4 (GeneID 55181).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ABC2 Antibody

Immunohistochemistry: ABC2 Antibody [NB100-74598] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-ABC2 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB staining using Immunohistochemistry Accessory Kit.
Immunohistochemistry-Paraffin: ABC2 Antibody [NB100-74598] - FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-ABC2 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit
Immunohistochemistry-Paraffin: ABC2 Antibody [NB100-74598] - FFPE section of human thyroid carcinoma. Antibody: Affinity purified rabbit anti-ABC2 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit

Applications for ABC2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:100-1:500

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
For Immunohistochemistry-Paraffin epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ABC2

ABC2 (amplified in breast cancer 2 gene) has been identified as a gene amplified and overexpressed in breast cancer. The specific function of ABC2 has not been reported.

Alternate Names

ABC2, Amplified in breast cancer gene 2 protein, chromosome 17 open reading frame 71, FLJ10587, protein SMG8, Protein smg-8 homolog, SMG8

Entrez Gene IDs

55181 (Human)

Gene Symbol

SMG8

UniProt

Additional ABC2 Products

Product Documents for ABC2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ABC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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