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6 results for "Trk Receptor Inhibitors Small Molecules and Peptides" in Products

Trk Receptor Inhibitors Small Molecules and Peptides

JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB

Alternate Names:
CEP-701
Chemical Name:
(9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
Purity:
≥98%
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB

Potent, selective TrkA inhibitor

Chemical Name:
1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one
Purity:
≥99%
Potent, selective TrkA inhibitor

Inhibits NGF binding to p75NTR and TrkA

Chemical Name:
2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde
Purity:
≥95%
Inhibits NGF binding to p75NTR and TrkA

Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

Chemical Name:
N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Purity:
≥98%
Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

Selective TrkB receptor agonist; neuroprotectant

Chemical Name:
N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide
Purity:
≥98%
Selective TrkB receptor agonist; neuroprotectant

Potent and selective pan-Trk inhibitor; peripherally restricted

Chemical Name:
N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide
Purity:
≥98%
Potent and selective pan-Trk inhibitor; peripherally restricted
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