5 results for "Toll-like Receptor Inhibitors" in Products
Toll-like Receptor Inhibitors Products
Toll-like receptors (TLRs) are single transmembrane cell-surface receptors, which have a key role in the innate immune system. TLRs generally exist as homodimers (although TLR2-TLR6 heterodimers have been reported) and are found on immune cells such as macrophages, B lymphocytes and mast cells.
Toll-like receptors are activated by molecules associated with biological threat and are highly specific towards evolutionarily conserved entities on microbes, such as bacterial cell-surface ...
TLR4 signaling inhibitor
| Chemical Name: | (R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate |
| Purity: | ≥98% (HPLC) |
TLR4 inhibitor
| Alternate Names: | TLR4-IN-C34 |
| Chemical Name: | 1-Methylethyl 2-(acetylamino)-2-deoxy-α-D-glucopyranoside 3,4,6-triacetate |
Autophagy inhibitor; also TLR9 inhibitor
| Chemical Name: | 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate |
| Purity: | ≥98% (HPLC) |
Selective TLR1/2 inhibitor
| Chemical Name: | 3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester |
| Purity: | ≥98% (HPLC) |
Highly potent TLR8 inhibitor
| Chemical Name: | 2-Methyl-4-(7-methoxy-4-quinolinyl)phenol |
| Purity: | ≥98% (HPLC) |
