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TGF-beta 1 Products

TGF-beta 1 (Transforming Growth Factor beta 1) is a pleiotrophic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta 1 associates with LAP to form a latent complex. It can be is activated from latency by plasmin, matrix metalloproteases, thrombospondin 1, and a subset of integrins. TGF-beta 1 signals through complexes of TGF-beta RII with TGF-beta RI/ALK-5 or ALK-1. TGF-beta signaling is modulated by the accessory receptors TGF-beta RIII/Betaglycan and Endoglin/CD105.

Reactivity:
Multi-Species
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, B/N
TGF-beta Pan Specific antibody in Human Prostate Tissue by Immunohistochemistry (IHC-P).
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