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58 results for "Smoothened" in Products
Smoothened Products
Smoothened, a Frizzled Receptor, is homologous to the Drosophila segment polarity Smo gene. It associates with the Patched protein to mediate the cellular response to the Hedgehog secreted protein signal, which controls patterning and growth during vertebrate development. Smoothened is activated in a number of human tumors and can function as an oncogene in basal-cell carcinomas. Smoothened expression has been documented in bladder, blood, brain, the central nervous system, skin, and ureter. ESTs have been isolated from amnion, bone, brain, breast, embryo, eye, heart, nerve, and skin libraries.
Chemical Name:
(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol
Purity:
≥97%
Reactivity:
Human, Mouse, Rat, Porcine, Bat, +6 More
Details:
Rabbit IgG Polyclonal
Applications:
IHC, ICC/IF
![Immunohistochemistry-Paraffin: Smoothened Antibody - BSA Free [NLS2666]](https://resources.rndsystems.com/images/products/Smoothened-Antibody-Immunohistochemistry-Paraffin-NLS2666-img0003.jpg "Immunohistochemistry-Paraffin: Smoothened Antibody - BSA Free [NLS2666]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA
![Western Blot: Smoothened Antibody [NBP3-06699]](https://resources.rndsystems.com/images/products/Smoothened-Antibody-Western-Blot-NBP3-06699-img0003.jpg "Western Blot: Smoothened Antibody [NBP3-06699]")
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1015418
Applications:
IHC
Chemical Name:
3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide dihydrochloride
Purity:
≥98%
Chemical Name:
1-[4-(5'-Chloro-3,5-dimethyl[2,4'-bipyridin]-2'-yl-1-piperazinyl]-3-(methylsulfonyl)-1-propanone hydrochloride
Purity:
≥98%
Chemical Name:
N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide]
Purity:
≥98%
Chemical Name:
4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
Purity:
≥98%
Alternate Names:
glasdegib,PF-913
Chemical Name:
1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt
Purity:
≥98%
Chemical Name:
rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
Purity:
≥98%
Reactivity:
Human
Source:
Wheat germ
Applications:
WB, ELISA, AP, Endotoxin, PAGE
![SDS-PAGE: Recombinant Human Smoothened GST (N-Term) Protein [H00006608-Q01]](https://resources.rndsystems.com/images/products/qc_test-H00006608-Q01-1.jpg "SDS-PAGE: Recombinant Human Smoothened GST (N-Term) Protein [H00006608-Q01]")
Reactivity:
Human
Source:
Wheat germ
Applications:
WB, ELISA, AP, Endotoxin
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1015418
Applications:
IHC
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1015418
Applications:
IHC
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1015418
Applications:
IHC
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1015418
Applications:
IHC
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1015418
Applications:
IHC
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1015418
Applications:
IHC
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1015418
Applications:
IHC
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #1015418
Applications:
IHC
Reactivity:
Human
Applications:
WB
![Western Blot: Smoothened Overexpression Lysate [NBP2-10451]](https://resources.rndsystems.com/images/products/Smoothened-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-10451-img0001.jpg "Western Blot: Smoothened Overexpression Lysate [NBP2-10451]")
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB
Reactivity:
Human
Source:
Wheat germ
Applications:
AP