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125 results for "SMAC/Diablo" in Products

SMAC/Diablo Products

SMAC (second mitochondria-derived activator of caspase)/Diablo, the mammalian functional homologue of Drosophila Hid, Grim, and Reaper, regulates apoptosis by neutralizing inhibitor of apoptosis (IAP) proteins. IAP family members contain one to three baculovirus IAP repeat (BIR) domains, each exhibiting distinct functions and caspase specificity. The BIR2 domain inhibits caspase-3 and –7, whereas the BIR3 domain inhibits caspase-9 activity. SMAC/Diablo interacts with BIR2 and BIR3 domains of IAPs, thereby neutralizing IAP inhibition and promoting caspase catalytic activity and apoptosis.

Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Western Blot: SMAC/Diablo Antibody [NB100-56311]
(2)
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Rabbit IgG Polyclonal

Recombinant Monoclonal Antibody

Reactivity: Human
Details: Rabbit IgG Monoclonal Clone #006
Applications: WB, ELISA, ICC/IF, Flow
Western Blot: SMAC/Diablo Antibody (006) [NBP2-89251]
(3)
Source: E. coli
Accession #: Q9NR28
Applications: InhibAct
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human
Details: Rabbit IgG Polyclonal
Reactivity: Human
Details: Rabbit IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Rabbit IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Rabbit IgG Polyclonal
Reactivity: Human
Details: Rabbit IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Goat IgG Polyclonal
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