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Slug Products

SLUG encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #666633
Applications:
Flow
Detection of Slug antibody in HeLa Human Cell Line antibody by Flow Cytometry.
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