788 results for "Siglec-2/CD22" in Products
Siglec-2/CD22 Products
Siglec-2 (sialic acid binding Ig-like lectin 2), also known as CD22, is a 130-140 kDa type I transmembrane glycoprotein with seven Ig-like domains in the extracellular region and three ITIM motifs in its cytoplasmic region. Alternate splicing generates an additional isoform that lacks the third and fourth Ig-like domains. Siglec-2 is expressed on B cells, preferentially binds alpha 2-6 linked sialic glycans including CD45 and mediates B cell - B cell interactions. Phosphorylation of Tyr822 within one of the ITIMs is important for Siglec-2 signal transduction through its association with the kinases Lyn, PI 3-Kinase p85 alpha, and SYK.
| Source: | NS0 |
| Accession #: | CAA42006 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | EHH59463 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P35329 |
| Applications: | BA |
Catalog #:
FAB19684AFP555
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219933 |
Catalog #:
AF2296AFP680
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Source: | CHO |
| Accession #: | CAA42006.1 |
| Applications: | BA |
Catalog #:
FAB19682AFP405
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #219903 |
Catalog #:
FAB19683AFP594
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #219919 |
Catalog #:
FAB19684AFP680
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219933 |
Catalog #:
FAB1968AFP405
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219934 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219902 |
| Applications: | WB |
Biotinylated
| Source: | CHO |
| Accession #: | CAA42006.1 |
| Applications: | BA, BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #219903 |
| Applications: | Neut |
Fc Chimera
| Source: | NS0 |
| Accession #: | CAA42006.1 |
| Applications: | BA |
Fc Chimera
| Source: | NS0 |
| Accession #: | CAA42006.1 |
| Applications: | BA |
Catalog #:
FAB19684AFP488
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219933 |
Catalog #:
LFAB10732AFP488
| Reactivity: | Human |
| Details: | Llama Monoclonal Clone #L007.2.5N |
Catalog #:
LFAB10732AFP680
| Reactivity: | Human |
| Details: | Llama Monoclonal Clone #L007.2.5N |
Catalog #:
FAB19681AFP405
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219902 |
Catalog #:
FAB1968AFP680
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219934 |
Catalog #:
FAB19683AFP405
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #219919 |