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14 results for "Progranulin/PGRN" in Products
Progranulin/PGRN Products
Progranulin, also known as Acrogranin, PCDGF, and Epithelin/Granulin Precursor, is a widely expressed glycoprotein that can undergo proteolysis to generate numerous Granulin peptides. Progranulin plays a role in the regulation of mesothelial differentiation, macrophage development, sexual differentiation of the brain, cartilage proliferation, wound repair, and the development of rheumatoid arthritis and osteoarthritis. It is often upregulated in cancer and contributes to tumor progression. Progranulin upregulation or mutation is associated with several neurological disorders including frontotemporal dementia, Creutzfeldt-Jakob disease, Alzheimer's disease, and motor neuron disease.
Reactivity:
Human
Assay Range:
62.5-4000 pg/mL
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
125-8000 pg/mL
Applications:
ELISA
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #333729
Applications:
ELISA(Det)
Reactivity:
Mouse
Details:
Sheep IgG Polyclonal
Applications:
WB
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #296628
Applications:
WB, IP
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #296605
Applications:
IHC, WB
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #296626
Applications:
ELISA
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #333731
Applications:
IHC, WB
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #296612
Applications:
ELISA
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #333729R
Applications:
ELISA
Reactivity:
Mouse
Details:
Rat IgG1 Monoclonal Clone #333708R
Applications:
ELISA
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #007
Applications:
ELISA
Reactivity:
Mouse
Details:
Rabbit IgG Monoclonal Clone #017
Applications:
ELISA