6 results for "PPAR alpha/NR1C1 Small Molecules and Peptides" in Products
PPAR alpha/NR1C1: Small Molecules and Peptides
Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family, termed peroxisome proliferator activated receptors (PPARs). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by ...
Highly selective, potent PPARα agonist. Orally active
| Chemical Name: | 2-[[4-[2-[[(Cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acid |
| Purity: | ≥98% (HPLC) |
Selective PPARα agonist
| Chemical Name: | [[4-Chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]acetic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective PPARγ agonist; antidiabetic agent
| Alternate Names: | BRL 49653 |
| Chemical Name: | 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Purity: | ≥98% (HPLC) |
PPARα/γ agonist
| Alternate Names: | AZ 242 |
| Chemical Name: | (S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid |
| Purity: | ≥98% (HPLC) |
PPARα antagonist
| Chemical Name: | N-((2S)-2-(((1Z)-1-Methyl-3-oxo-3-(4-(trifluoromethyl)phenyl)prop-1-enyl)amino)-3-(4-(2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy)phenyl)propyl)propanamide |
| Purity: | ≥98% (HPLC) |
RXR agonist
| Alternate Names: | DHA |
| Chemical Name: | (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoic acid |
| Purity: | ≥98% |
