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Noggin Products

Noggin is a secreted homodimeric antagonist of bone morphogenetic proteins (BMPs). It binds BMP-4 with high affinity and BMP-7 with lower affinity. Noggin regulates BMP activity in neural tube formation, somite patterning, cardiomyocyte development, and skeletal joint formation. Mutations of human Noggin are linked to multiple types of skeletal dysplasias that result in apical joint fusions. Noggin is expressed in defined areas of the adult central nervous system and peripheral tissues such as lung, skeletal muscle and skin. Noggin may also regulate the differentiation of embryonic stem cells into dopaminergic neurons.

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128 results for "Noggin" in Products

128 results for "Noggin" in Products

Noggin Products

Noggin is a secreted homodimeric antagonist of bone morphogenetic proteins (BMPs). It binds BMP-4 with high affinity and BMP-7 with lower affinity. Noggin regulates BMP activity in neural tube formation, somite patterning, cardiomyocyte development, and skeletal joint formation. Mutations of human Noggin are linked to multiple types of skeletal dysplasias that result in apical joint fusions. Noggin is expressed in defined areas of the adult central nervous system and peripheral tissues such as lung, skeletal muscle and skin. Noggin may also regulate the differentiation of embryonic stem cells into dopaminergic neurons.

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Analyzed by SEC-MALS

Source: NS0
Accession #: Q13253
Applications: BA
(6)
Source: NS0
Accession #: Q13253
Applications: BA
Graph showing bioactivity of human Noggin protein
Source: NS0
Accession #: Q13253.1
Applications: BA
Recombinant Human Noggin Fc Chimera GMP Protein Bioactivity
(2)
Source: NS0
Accession #: Q13253.1
Applications: BA
Recombinant Human Noggin GMP Protein Bioactivity
(2)
Source: E. coli
Accession #: Q13253.1
Applications: BA
(3)

Analyzed by SEC-MALS

Source: NS0
Accession #: P97466
Applications: BA
(2)
Source: E. coli
Accession #: P97466.1
Applications: BA
(2)
Reactivity: Human, Mouse, Rat
Details: Mouse IgG2B Monoclonal Clone #OTI1H8
Applications: IHC, WB, ICC/IF
Western Blot: Noggin Antibody (OTI1H8)Azide and BSA Free [NBP2-73030]
(6)
Source: E. coli
Accession #: Q13253.1
Applications: BA
(2)
Source: NS0
Accession #: P97466
Applications: BA
Graph showing dose-dependent bioactivity of mouse Noggin protein
Reactivity: Human, Mouse, Rat
Details: Mouse IgG2B Monoclonal Clone #OTI1H8
Applications: IHC, WB, ICC/IF
Western Blot: Noggin Antibody (OTI1H8) [NBP1-47881]
(6)
Reactivity: Human
Details: Mouse IgG2b Kappa Monoclonal Clone #4A1
Applications: WB, ELISA
Western Blot: Noggin Antibody (4A1) [H00009241-M04]
(2)
Reactivity: Human, Mouse, Rat
Details: Mouse IgG2b Kappa Monoclonal Clone #A9
Applications: IHC, WB
Noggin Antibody (A9)
(3)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC
Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]
(4)
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