110 results for "Nicalin" in Products
Nicalin Products
Nicastrin is an integral part of the Alzheimers associated gamma-secretase complex. Nicalin, a Nicastrin-like protein, is not associated with gamma-secretase but rather interacts with NOMO (Nodal modulator). Nodals are TGFbeta signaling factors that control various cell fate decisions during embryonic body planning stages in vertebrate development. The Nicalin/NOMO complex acts to regulate the Nodal signaling factors during gastrulation. This regulation most often affects the development of the axial mesoderm. Nodal signaling is an important factor for melanoma cell invasiveness and tumorigenicity and inhibition of this signal can promote melanoma cells reverting back toward a melanocyte phenotype.
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Western Blot: Nicalin Antibody [NBP1-81002]](https://resources.bio-techne.com/images/products/Nicalin-Antibody-Western-Blot-NBP1-81002-img0004.jpg "Western Blot: Nicalin Antibody [NBP1-81002]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Nicalin AntibodyBSA Free [NBP2-81860]](https://resources.bio-techne.com/images/products/Nicalin-Antibody-Western-Blot-NBP2-81860-img0001.jpg "Western Blot: Nicalin AntibodyBSA Free [NBP2-81860]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Nicalin Antibody [NBP2-19494]](https://resources.bio-techne.com/images/products/Nicalin-Antibody-Western-Blot-NBP2-19494-img0002.jpg "Western Blot: Nicalin Antibody [NBP2-19494]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Nicalin Antibody [NBP2-19493]](https://resources.bio-techne.com/images/products/Nicalin-Antibody-Western-Blot-NBP2-19493-img0002.jpg "Western Blot: Nicalin Antibody [NBP2-19493]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Nicalin Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp2-81860cl1_rabbit-nicalin-pab-corafluor-1-8920251145128.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
![Nicalin Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/af7686cl1_sheep-nicalin-pab-corafluor-1-12920251273323.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Nicalin Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-18435cl1_rabbit-nicalin-pab-corafluor-1-89202515533017.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |