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Mitosis Inhibitors: Small Molecules and Peptides

Mitosis is a highly complex and regulated sequence of events that occurs exclusively in eukaryotic cells and produces two identical daughter cells from a single parent cell.

Mitosis is split into five phases:

  1. Prophase - Chromatin condenses to form chromosomes. Centrosomes begin to migrate to opposite poles of the cell.
  2. Prometaphase - The nuclear envelope breaks down and centrosomes are situated at opposite poles of the cell. Sister chromatids attach to the microtubule spindles.
  3. ...
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Cell-permeable APC/C inhibitor

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