MeCP2 Products
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
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83 results for "MeCP2" in Products
83 results for "MeCP2" in Products
MeCP2 Products
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MeCP2 Antibody [NB100-56326]](https://resources.bio-techne.com/images/products/MeCP2-Antibody-Western-Blot-NB100-56326-img0002.jpg "Western Blot: MeCP2 Antibody [NB100-56326]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: MeCP2 Antibody [NB600-1101]](https://resources.bio-techne.com/images/products/MeCP2-Antibody-Western-Blot-NB600-1101-img0006.jpg "Western Blot: MeCP2 Antibody [NB600-1101]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1B11 |
| Applications: | IHC, WB, ELISA |
![Western Blot: MeCP2 Antibody (1B11) [H00004204-M03]](https://resources.bio-techne.com/images/products/MeCP2-Antibody-1B11-Western-Blot-H00004204-M03-img0009.jpg "Western Blot: MeCP2 Antibody (1B11) [H00004204-M03]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #4B6 |
| Applications: | IHC, WB, ELISA |
![Western Blot: MeCP2 Antibody (4B6) [H00004204-M01]](https://resources.bio-techne.com/images/products/MeCP2-Antibody-4B6-Western-Blot-H00004204-M01-img0012.jpg "Western Blot: MeCP2 Antibody (4B6) [H00004204-M01]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunohistochemistry-Paraffin: MeCP2 Antibody [NBP1-81027]](https://resources.bio-techne.com/images/products/MeCP2-Antibody-Immunohistochemistry-Paraffin-NBP1-81027-img0014.jpg "Immunohistochemistry-Paraffin: MeCP2 Antibody [NBP1-81027]")
| Reactivity: | Human, Mouse, Rat, Monkey |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MeCP2 Antibody [NBP2-50060]](https://resources.bio-techne.com/images/products/MeCP2-Antibody-Western-Blot-NBP2-50060-img0005.jpg "Western Blot: MeCP2 Antibody [NBP2-50060]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #5H12 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MeCP2 Antibody (5H12) [NBP2-60787]](https://resources.bio-techne.com/images/products/MeCP2-Antibody-5H12-Western-Blot-NBP2-60787-img0001.jpg "Western Blot: MeCP2 Antibody (5H12) [NBP2-60787]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![MeCP2 [p Ser80] Antibody](https://resources.bio-techne.com/images/products/nbp3-23406_rabbit-mecp2-p-ser80-pab-19920231252361.jpg "Western Blot: MeCP2 [p Ser80] Antibody [NBP3-23406] -")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: MeCP2 Antibody [NBP1-81028]](https://resources.bio-techne.com/images/products/MeCP2-Antibody-Immunohistochemistry-Paraffin-NBP1-81028-img0012.jpg "Immunohistochemistry-Paraffin: MeCP2 Antibody [NBP1-81028]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![MeCP2 [p Ser421] Antibody](https://resources.bio-techne.com/images/products/nbp3-23407_rabbit-mecp2-p-ser421-pab-1992023191543.jpg "Western Blot: MeCP2 [p Ser421] Antibody [NBP3-23407] -")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: MeCP2 [p Ser421] Antibody [NBP2-29524]](https://resources.bio-techne.com/images/products/MeCP2-[p-Ser421]-Antibody-Western-Blot-NBP2-29524-img0001.jpg "Western Blot: MeCP2 [p Ser421] Antibody [NBP2-29524]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB, ICC/IF |
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| Applications: | ELISA |
![Western Blot: MeCP2 Overexpression Lysate [NBL1-12977]](https://resources.bio-techne.com/images/products/MeCP2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12977-img0002.jpg "Western Blot: MeCP2 Overexpression Lysate [NBL1-12977]")
| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +2 More |
| Details: | Mouse IgG1 Monoclonal Clone #4F11 |
| Applications: | IHC, WB, ICC/IF |
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| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +2 More |
| Details: | Mouse IgG1 Monoclonal Clone #4F11 |
| Applications: | IHC, WB, ICC/IF |
![MeCP2 Antibody (4F11) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-05541cl1_mouse-mecp2-mab-4f11-corafluor-1-29920251454160.png "Product Feature: CoraFluor Probes for TR-FRET")
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| Reactivity: | Human, Mouse, Rat, Monkey |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB, ICC/IF |
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| Reactivity: | Human, Mouse, Rat, Monkey |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB, ICC/IF |
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| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +2 More |
| Details: | Mouse IgG1 Monoclonal Clone #4F11 |
| Applications: | IHC, WB, ICC/IF |
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