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6 results for "M-CSF R/CD115" in Products

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M-CSF R/CD115 Products

Macrophage Colony-Stimulating Factor Receptor (M-CSF R), also known as Colony Stimulating Factor 1 Receptor (CSF1 R) and CD115, is a cell-surface protein that serves as a receptor for the cytokines M-CSF and IL-34. It is a member of the type III subfamily of receptor tyrosine kinases. Human M-CSF R/CD115 is 972 amino acids (aa) in length with a predicted molecular weight of approximately 108 kDa, and shares 60% and 64% aa sequence identity with the mouse and rat orthologs, respectively. It is a ...

Ki 20227

Catalog #: 4481

Citations (14)

Product Documents

Images (1)

c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation

Chemical Name:

N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea

Purity:

≥97%

AC 710

Catalog #: 5013

Citations (5)

Product Documents

Images (1)

Potent and selective PDGFR family inhibitor

Chemical Name:

N-[4-[[[[5-(1,1-Dimethethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)oxy]-2-pyridinecarboxamide

Purity:

≥98%

Src I1

Catalog #: 3642

Citations (9)

Product Documents

Images (1)

Dual site Src kinase inhibitor

Chemical Name:

6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine

Purity:

≥98%

Sunitinib malate

Catalog #: 3768

Citations (11)

Product Documents

Images (1)

Potent VEGFR, PDGFRβ and KIT inhibitor

Alternate Names:

SU 11248

Chemical Name:

N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt

Purity:

≥98%