Lactate Dehydrogenase A/LDHA: Small Molecules and Peptides
Lactate Dehydrogenase A is also known as LDHA, LDH5, and EC 1.1.1.27. It is one of five isoforms of the lactate dehydrogenase family. LDHA catalyzes the conversion of pyruvate into lactate under anaerobic conditions. It is also a key component in the altered glycolytic metabolism that is a feature of cancer cells.
Products:
3 results for "Lactate Dehydrogenase A/LDHA Small Molecules and Peptides" in Products
3 results for "Lactate Dehydrogenase A/LDHA Small Molecules and Peptides" in Products
Lactate Dehydrogenase A/LDHA: Small Molecules and Peptides
Lactate Dehydrogenase A is also known as LDHA, LDH5, and EC 1.1.1.27. It is one of five isoforms of the lactate dehydrogenase family. LDHA catalyzes the conversion of pyruvate into lactate under anaerobic conditions. It is also a key component in the altered glycolytic metabolism that is a feature of cancer cells.
Products:
Potent lactate dehydrogenase Degrader (PROTAC®)
| Chemical Name: | 2-(5-(Cyclopropylmethyl)-3-(3-(6-(13-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-13-oxotridecanamido)hex-1-yn-1-yl)phenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid |
| Purity: | ≥98% (HPLC) |
Potent and selective LDHA inhibitor
| Chemical Name: | 3-[[3-[(Cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)benzoic acid |
| Purity: | ≥98% (HPLC) |
LDHA inhibitor
| Chemical Name: | Methyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate |
| Purity: | ≥98% (HPLC) |
