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4 results for "Klotho beta" in Products

Klotho beta Products

Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to  FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.

Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, ICC/IF
Reactivity:
Human
Details:
Mouse IgG2A Monoclonal Clone #885935
Applications:
WB

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #1025C
Applications:
Flow
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